Prepare Cajun Spice Mix by combining paprika, garlic powder, onion powder, oregano, thyme, black pepper, cayenne pepper, and white pepper in a small bowl.

Heat a large skillet over medium-high heat, add olive oil, then sprinkle half of the prepared Cajun spice mix and sauté for about 1 minute.

Season both sides of the chicken breasts with the remaining spices, cook for 5-7 minutes on each side until golden brown, then remove and let rest.

In the same skillet, bring salted water to a boil and cook penne pasta according to package instructions until al dente.

Lower the heat to medium and sauté minced garlic in residual oil for 1 minute, then add heavy cream and chicken broth.

Simmer for 3-4 minutes until the sauce thickens, stir in Parmesan cheese until melted.

Slice the seared chicken and return it to the skillet, tossing gently to coat.

Add the drained pasta to the skillet, folding gently into the sauce for 1-2 minutes, then serve warm.